The paper uses the history of the entanglement of the Mi'kmaq peoples and newly arrived French settlers during the 17th and 18th centuries, in what is known today as Canada's Maritime provinces, as a case study of key themes from the theory of entangled political economy. A new political economy, identified as Acadia, emerged from the economic and social interaction of the two peoples, and formed the basis for a sustained political economy that lasted close to a century. Radical disruption from external forces -- esp. the French and English competition to control the eastern portions of North America -- led to catastrophe for the continued existence of Acadia. Historical attention has most often been focused on the political competition between Great Britain and France and the inevitability of Acadia's failure in the clash of great powers. Here, attention will be focused on the Ostromian and Wagnerian themes that might help us understand how Acadian society was created as a radically entangled society in a space created by the absence/presence of great powers.